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- Title
Endometrial polyps: when to resect?
- Authors
Azevedo, Julia; Azevedo, Ligia; Freitas, Fernando; Wender, Maria; de Azevedo, Julia Marques da Rocha; de Azevedo, Ligia Marques da Rocha; Wender, Maria Celeste Osorio
- Abstract
<bold>Purpose: </bold>To determine the prevalence of malignant and premalignant endometrial polyps and to investigate the association of malignancy with specific factors.<bold>Methods: </bold>This is a retrospective study of women submitted to hysteroscopic resection of endometrial polyps between January 2005 and July 2013 at a university hospital in southern Brazil. Data regarding clinical characteristics and pathology findings were collected from patient charts.<bold>Results: </bold>Of 359 patients, 87.2% had benign polyps and 9.9% had hyperplasia without atypia. Atypical hyperplasia was found in 2.6% of the sample. Endometrial adenocarcinoma was found in one woman (0.3%). A correlation was observed between malignant/premalignant polyps and patient age, menopausal status, and uterine bleeding. All patients with malignancies/premalignancies had abnormal uterine bleeding. Higher frequency of malignant polyps was observed in tamoxifen users, however, without statistical significance (p = 0.059%). Malignancy was not correlated with arterial hypertension, diabetes mellitus, obesity, hormone therapy, endometrial thickness, and polyp diameter.<bold>Conclusions: </bold>Malignant/premalignant findings had low prevalence and were absent in asymptomatic patients. From the data of this retrospective study, it is unclear whether routine polypectomy should be performed in asymptomatic patients. Further prospective studies including larger numbers of patients are required to guide treatment recommendations.
- Subjects
BRAZIL; DIAGNOSIS of endometrial cancer; TREATMENT of endometrial cancer; POLYPECTOMY; RETROSPECTIVE studies; STATISTICAL significance; HYPERPLASIA; AGE distribution; HYSTEROSCOPY; MENOPAUSE; POLYPS; PRECANCEROUS conditions; UTERINE hemorrhage; UTERINE tumors; ENDOMETRIAL tumors; DISEASE prevalence; SURGERY
- Publication
Archives of Gynecology & Obstetrics, 2016, Vol 293, Issue 3, p639
- ISSN
0932-0067
- Publication type
journal article
- DOI
10.1007/s00404-015-3854-3