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- Title
P-hacking can be avoided with core outcome sets: preterm birth research is ready to take this leap.
- Authors
Hooft, J; Khan, KS; Van't Hooft, J; Khan, K S
- Abstract
The article by Thornton et al. establishes with data from progestogen trials something we have always feared, i.e. the corruption of reported results through selective publication of outcomes. In their analysis, trials with a predefined primary outcome showed no effect of progesterone consistently; trials that did not report a predefined primary outcome, however, had a tendency to show more promising results. Indeed this problem is so ingrained that even prospective registration of trials has not fully addressed it. This article is protected by copyright. All rights reserved.
- Subjects
PREMATURE labor; LABOR complications (Obstetrics); CLINICAL trials; PROGESTERONE; CERVICAL cerclage; LOW birth weight; PREMATURE infants; EVALUATION of medical care; PREGNANCY; PROGESTATIONAL hormones; RESEARCH
- Publication
BJOG: An International Journal of Obstetrics & Gynaecology, 2017, Vol 124, Issue 7, p1017
- ISSN
1470-0328
- Publication type
journal article
- DOI
10.1111/1471-0528.14647