We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Nefrotoxicitatea medicamentelor: mecanisme și biomarkeri.
- Authors
Bacinschi, Nicolae; Guțu, Ina; Caracaș, Anastasia; Vasilache, Eugenia
- Abstract
The increasing incidence of drug-related renal pathology represents a pressing problem for medical specialties and clinical pharmacology, which requires a multilateral approach. The elucidation and analysis of the mechanisms of drug nephrotoxicity, the processes that influence them and the specific biomarkers that allow the early detection of reversible renal lesions will significantly reduce the undesirable consequences of the drugs on the kidneys. The review of nephrotoxic drugs and of the responsible pathogenic mechanisms will allow the development of principles for monitoring, prevention and correction of renal disorders, which will complement the pharmacovigilance compartment of clinical pharmacology.
- Subjects
CLINICAL pharmacology; MEDICAL specialties &; specialists; DRUG analysis; PHARMACOLOGY; NEPHROTOXICOLOGY; BIOLOGICAL tags; PROXIMAL kidney tubules
- Publication
Farmacist.ro, 2020, Issue 2, p30
- ISSN
1584-6539
- Publication type
Article