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- Title
New reactions of benzocaine.
- Authors
Azev, Yu.; Ermakova, O.; Berseneva, V.; Bakulev, V.
- Abstract
Reaction of benzocaine with indane-1,3-dione-2-carbaldehyde afforded the corresponding azomethine. Ethoxymethylenemalonate reacted with benzocaine to form ethyl 4-{[2-(ethoxycarbonyl)-4-methoxy-3-oxobuten-1-yl]amino}benzoate, which was converted to the corresponding quinolone when heated to 185-190°C. Reactions of benzocaine with aliphatic aldehydes furnished 2,3-alkyl-substituted quinolines.
- Subjects
BENZOCAINE; SCHIFF bases; QUINOLONE antibacterial agents; ALDEHYDES; AROMATIC amines
- Publication
Russian Journal of General Chemistry, 2016, Vol 86, Issue 11, p2442
- ISSN
1070-3632
- Publication type
Article
- DOI
10.1134/S1070363216110074