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- Title
Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Subvariant Neutralization Following a Primary Vaccine Series of NVX-CoV2373 and BNT162b2 Monovalent Booster Vaccine.
- Authors
Babu, Tara M; Shen, Xiaoying; McClelland, R Scott; Wang, Zijun; Selke, Stacy; Wilkens, Chloe; Hauge, Kirsten A; McClurkan, Christopher L; Goecker, Erin; Laing, Kerry J; Koelle, David M; Greninger, Alexander L; Nussenzweig, Michel C; Montefiori, David C; Corey, Lawrence; Wald, Anna
- Abstract
We evaluated the immunologic response to a novel vaccine regimen that included 2 doses of NVX-CoV2373 (Novavax) followed by 1 dose of BNT162b2 (Pfizer-BioNTech) monovalent booster vaccine. A durable neutralizing antibody response to Omicron BA.4/BA.5 and BA.1 variants was observed at month 6 after the booster, while immune escape was noted for the XBB.1.5 variant.
- Subjects
SARS-CoV-2; BOOSTER vaccines; SARS-CoV-2 Omicron variant; COVID-19 vaccines; VACCINES
- Publication
Open Forum Infectious Diseases, 2024, Vol 11, Issue 2, p1
- ISSN
2328-8957
- Publication type
Case Study
- DOI
10.1093/ofid/ofad673