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- Title
Studies of the sensitizing properties of propolis.
- Authors
Acciai, M. C.; Ginanneschi, M.; Bracci, S.; Sertoli, A.
- Abstract
As suggested by recent studies, the main contact allergen of propolis is dimethylallyl ester of caffiec acid. This ester is a phenolic compound that can be transformed through oxidation of the OH groups into ortho or paraquinones, which would become the effective allergens. This hypothesis is verified in the article by synthesizing dimethylallyl ester of caffeic acid together with its 0-methyl derivatives, with partially or completely blocked hydroxylic functions. The structure and purity of these products were confirmed by analytical and spectroscopic data.
- Subjects
PROPOLIS; BEE products; ALLERGENS; ESTERS; HYDROXYLATION; HYDROFORMYLATION
- Publication
Contact Dermatitis (01051873), 1990, Vol 23, Issue 4, p274
- ISSN
0105-1873
- Publication type
Article
- DOI
10.1111/j.1600-0536.1990.tb05099.x