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- Title
Association between the MTHFR C677T Polymorphism and Breast Cancer Risk: A Meta-Analysis of 23 Case-Control Studies.
- Authors
Yan, Wanjun; Zhang, Yafei; Zhao, Enfa; Zhang, Shuqun
- Abstract
The article presents a meta-analysis to explore association between methylenetetrahydrofolate (MTHFR) C677T polymorphism and breast cancer risks. It mentions that the meta-analysis include 23 studies with 6,564 breast cancer cases and 7,801 case-free controls. Topics discussed include risks of breast cancer as per stratification of age, and environmental factors; mechanism of breast carcinogenesis and the role of C677T polymorphism in breast cancer especially in Caucasians.
- Subjects
BREAST tumor risk factors; FOLIC acid metabolism; BREAST tumors; FOLIC acid deficiency; GENETIC polymorphisms; META-analysis; OXIDOREDUCTASES; CASE-control method; DESCRIPTIVE statistics; ODDS ratio; DISEASE complications; EVALUATION
- Publication
Breast Journal, 2016, Vol 22, Issue 5, p593
- ISSN
1075-122X
- Publication type
Article
- DOI
10.1111/tbj.12639