We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Psoriasiform dermatitis following ocrelizumab in relapsing-remitting multiple sclerosis: Case report and literature review.
- Authors
Emma, Callanan; Vesela, Petkova; Kay, Polly; Huseyin, Huseyin; Alison, Hassett; Mara, Sittampalam; Floriana, De Angelis; Sara, Collorone
- Abstract
We present a case of a 30-year-old man with relapsing-remitting multiple sclerosis who developed psoriasiform dermatitis following his second course of ocrelizumab. This resolved with topical therapies and discontinuation of treatment. Cases of psoriasiform rashes have been increasingly reported in the use of ocrelizumab and are possibly due to B-cell (CD20) depletion and T-cell overregulation. Nevertheless, skin-related adverse reactions are not yet considered in the risk management plans of anti-CD20 treatments in multiple sclerosis.
- Subjects
LITERATURE reviews; MULTIPLE sclerosis; DISEASE relapse; SKIN inflammation; DRUG side effects; JOHN Cunningham virus
- Publication
Multiple Sclerosis Journal, 2024, Vol 30, Issue 7, p893
- ISSN
1352-4585
- Publication type
Article
- DOI
10.1177/13524585241232277