We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Comparison of MOG and AQP4 antibody seroprevalence in Korean adults with inflammatory demyelinating CNS diseases.
- Authors
Hyun, Jae-Won; Lee, Hye Lim; Jeong, Woo Kyo; Lee, Hye Jung; Shin, Jong Hwa; Min, Ju-Hong; Kim, Byoung Joon; Kim, Seung Woo; Shin, Ha Young; Oh, Jeeyoung; Kim, Woojun; Shin, Hyun-June; Oh, Sun-Young; Kim, Hyunjin; Lim, Young-Min; Huh, So-Young; Cho, Eun Bin; Nam, Tai-Seung; Lee, Seung-Han; Kim, Sun-Young
- Abstract
We aimed to compare seroprevalence of anti-myelin oligodendrocyte glycoprotein (MOG) and anti-aquaporin-4 (AQP4) antibodies in Korean adults with inflammatory demyelinating diseases (IDDs) of the central nervous system (CNS), based on a multicenter nationwide database. Sera were analyzed using a live cell–based assay for MOG and AQP4 antibodies. Of 586 Korean adults with IDDs of the CNS, 36 (6.1%) and 185 (31.6%) tested positive for MOG and AQP4 antibodies, respectively. No participant showed double positivity. Seroprevalence of MOG antibodies was about five times lower than that of AQP4 antibodies in a large cohort of Korean adults with IDDs of the CNS.
- Subjects
KOREANS; DEMYELINATION; MYELIN sheath diseases; SEROPREVALENCE; IMMUNOGLOBULINS; CENTRAL nervous system
- Publication
Multiple Sclerosis Journal, 2021, Vol 27, Issue 6, p964
- ISSN
1352-4585
- Publication type
Article
- DOI
10.1177/1352458520948213