We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
LupusQoL-FR is valid to assess quality of life in patients with systemic lupus erythematosus.
- Authors
Devilliers, Hervé; Amoura, Zahir; Besancenot, Jean-Francois; Bonnotte, Bernard; Pasquali, Jean-Louis; Wahl, Denis; Maurier, Francois; Kaminsky, Pierre; Pennaforte, Jean-Loup; Magy-Bertrand, Nadine; Arnaud, Laurent; Binquet, Christine; Guillemin, Francis
- Abstract
Objective. To cross-culturally adapt the LupusQoL into French, to test its measurement properties and to further investigate its domain structure.Methods. The cultural adaptation process according to guidelines and pre-testing resulted in the LupusQoL-FR. SLE patients completed the LupusQoL-FR at baseline, 15 days, 3 months and 6 months. Validity was studied through content and construct validity (factorial and Rasch analysis for structural validity, Spearman’s correlation and Mann–Whitney tests for external validity). Cronbach’s α and intra-class correlation coefficients were computed for reliability. The standardized response mean was computed to evaluate responsiveness.Results. In all, 182 patients, age 39.6 (10.6) years, mostly outpatients [mean SELENA-SLEDAI 2.6 (3.5)] were recruited. Factor analysis with eight imposed factors was very close to the original LupusQoL. A screeplot with parallel analysis showed that LupusQoL domains could be aggregated in two physical and mental scales. Both eight- and two-factor structures showed a good Rasch fit, internal consistency (Cronbach’s α: 0.85–0.95), and test–retest reliability (intra-class correlation coefficient 0.79–0.95). External convergent (correlation with SF-36, r = 0.59–0.78) and divergent validity (according to SELENA-SLEDAI) were also satisfactory.Conclusion. The LupusQoL-FR is valid to assess quality of life in SLE patients. A two-factor structure of physical and mental aggregated scales is a valid alternative to the original eight-domain structure.
- Subjects
FRANCE; SYSTEMIC lupus erythematosus; ACADEMIC medical centers; STATISTICAL correlation; HEALTH surveys; LONGITUDINAL method; MEDICAL cooperation; HEALTH outcome assessment; PSYCHOMETRICS; QUALITY of life; RESEARCH; RESEARCH evaluation; RESEARCH funding; SCALE analysis (Psychology); STATISTICS; U-statistics; DATA analysis; VISUAL analog scale; TREATMENT effectiveness; INTER-observer reliability; DATA analysis software; DESCRIPTIVE statistics; PROGNOSIS
- Publication
Rheumatology, 2012, Vol 51, Issue 10, p1906
- ISSN
1462-0324
- Publication type
Article
- DOI
10.1093/rheumatology/kes165