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- Title
Combination of heparin and aspirin is superior to aspirin alone in enhancing live births in patients with recurrent pregnancy loss and positive anti-phospholipid antibodies: a meta-analysis of randomized controlled trials and meta-regression.
- Authors
Mak, Anselm; Cheung, Mike W.-L.; Cheak, Alicia Ai-cia; Ho, Roger Chun-man
- Abstract
Objective. The combination of heparin and aspirin was regarded as the ‘standard therapy’ for patients with recurrent pregnancy loss (RPL) and positive aPL antibodies to enhance live births, but it largely stems from expert opinion. We performed a meta-analysis of randomized controlled trials (RCTs) to assess whether this combination works better than aspirin alone.
- Subjects
HEPARIN; ASPIRIN; MISCARRIAGE; PREGNANCY complications; OBSTETRICS
- Publication
Rheumatology, 2010, Vol 49, Issue 2, p281
- ISSN
1462-0324
- Publication type
Article
- DOI
10.1093/rheumatology/kep373