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- Title
Plant-Derived (Poly)phenols and Their Metabolic Outcomes: The Pursuit of a Role for the Gut Microbiota.
- Authors
Freitas, Perla Lopes de; Miranda, João Paulo Nascimento; França, Lucas Martins; Paes, Antonio Marcus de Andrade
- Abstract
Plant-derived (poly)phenolic compounds have been undoubtedly shown to promote endocrine homeostasis through the improvement of diverse metabolic outcomes. Amongst diverse potential mechanisms, the prebiotic modulatory effects exerted by these compounds on the gut microbiota have supported their nutraceutical application in both experimental and clinical approaches. However, the comprehension of the microbiota modulatory patterns observed upon (poly)phenol-based dietary interventions is still in its infancy, which makes the standardization of the metabolic outcomes in response to a given (poly)phenol a herculean task. Thus, this narrative review sought to gather up-to-date information on the relationship among (poly)phenols intake, their modulatory effect on the gut microbiota diversity, and consequent metabolic outcomes as a supportive tool for the future design of experimental approaches and even clinical trials.
- Subjects
HOMEOSTASIS; FUNCTIONAL foods; POLYPHENOLS; PREBIOTICS; GUT microbiome; TREATMENT effectiveness; PLANT extracts
- Publication
Nutrients, 2022, Vol 14, Issue 17, p3510
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu14173510