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- Title
Multidrug-Resistant Tuberculosis Among Patients in Baja California, Mexico, and Hispanic Patients in California.
- Authors
Bojorquez, Ietza; Barnes, Richard F. W.; Flood, Jennifer; López-Gatell, Hugo; Garfein, Richard S.; Bäcker, Claudia E.; Alpuche, Celia; Vinetz, Joseph M.; Catanzaro, Antonino; Kato-Maeda, Midori; Rodwell, Timothy C.
- Abstract
Objectives. We sought to compare prevalence and determinants of multidrug-resistant tuberculosis (MDR-TB) between tuberculosis patients in Baja California, Mexico, and Hispanic patients in California. Methods. Using data from Mexico's National TB Drug Resistance Survey (2008-2009) and California Department of Public Health TB case registry (2004--2009), we assessed differences in MDR-TB prevalence comparing (1) Mexicans in Baja California, (2) Mexico-born Hispanics in California, (3) US-born Hispanics in California, and (4) California Hispanics born elsewhere. Results. MDR-TB prevalence was 2.1% in Baja California patients, 1.6% in Mexico-born California patients, 0.4% in US-born California patients, and 2.7% in Hispanic California patients born elsewhere. In multivariate analysis, previous antituberculosis treatment was associated with MDR-TB (odds ratio [OR] = 6.57; 95% confidence interval [CI] = 3.34, 12.96); Mexico-born TB patients in California (OR = 5.08; 95% CI = 1.19, 21.75) and those born elsewhere (OR = 7.69; 95% CI = 1.71, 34.67) had greater odds of MDR-TB compared with US-born patients (reference category). Conclusions. Hispanic patients born outside the US or Mexico were more likely to have MDR-TB than were those born within these countries. Possible explanations include different levels of exposure to resistant strains and inadequate treatment.
- Subjects
CALIFORNIA; MEXICO; CONFIDENCE intervals; DRUG resistance; EPIDEMIOLOGY; HISPANIC Americans; MULTIVARIATE analysis; RESEARCH funding; SURVEYS; TUBERCULOSIS; LOGISTIC regression analysis; DATA analysis; DATA analysis software; DESCRIPTIVE statistics
- Publication
American Journal of Public Health, 2013, Vol 103, Issue 7, p1301
- ISSN
0090-0036
- Publication type
Article
- DOI
10.2105/AJPH.2012.301039