We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Mycotic corneal ulcers caused by Fusarium spp. - available therapeutic option.
- Authors
Trojacka, Ewelina; Izdebska, Justyna; Wróblewska, Marta; Sulik-Tyszka, Beata; Ciepiaszuk, Karolina; Szaflik, Jacek P.
- Abstract
Fungal corneal ulcers caused by Fusarium spp. are known as sight threatening infection with bad course. Fungus properties, diagnostic difficulties and limited therapeutic ways result in poor outcomes. Three of antimycotic drugs are effective against Fusarium spp.: natamycin, amphotericin B and voriconazole. Natamycin is the only drug approved by FDA (Food and Drug Administration) for treatment of corneal ulcers caused by Fusarium spp. Fungistatic work and limited ocular penetration of antimycotic drugs lead to therapeutic keratoplasty in cases with extremely bad course. Patient with recurrent infections and very advanced inflammation, require enucleation. Currently there is no gold standard way of therapy for Fusarium spp. corneal ulcers.
- Subjects
MYCOSES; CORNEAL ulcer; NATAMYCIN; VORICONAZOLE; CORNEA surgery
- Publication
Acta Ophthalmologica Polonica / Klinika Oczna, 2021, Vol 123, Issue 3, p108
- ISSN
0023-2157
- Publication type
Article
- DOI
10.5114/ko.2021.107300