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- Title
A 'benign' malignant disease—splenic lymphoma with villous lymphocytes.
- Authors
Schattner, Ami; Dubin, Ina; Glick, Yair; Cohen, Yossi
- Abstract
It is histologically indistinguishable from splenic marginal-zone lymphoma and villous lymphocytes have immunologic and immunophenotypical characters of marginal zone lymphocytes.[2] Clinically, moderate lymphocytosis, villous lymphocytes on peripheral blood smear, marked splenomegaly, no lymphadenopathy, serum monoclonal band and a slow benign course are typical. Blood smear demonstrated abundant atypical lymphocytes with villous projections (Figure 1B). Imaging revealed massive splenomegaly (homogeneous) occupying most of the abdominal cavity (Figure 1A).
- Subjects
LYMPHOCYTES; LYMPHOMAS; LEUCOCYTES; NON-Hodgkin's lymphoma; INFORMED consent (Medical law); SPLENIC rupture
- Publication
QJM: An International Journal of Medicine, 2023, Vol 116, Issue 6, p445
- ISSN
1460-2725
- Publication type
Article
- DOI
10.1093/qjmed/hcad007