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- Title
Allosteric regulation of Glycogen Synthase and Hexokinase by Glucosamine-6-Phosphate During Glucosamine-Induced Insulin Resistance in Skeletal Muscle and Heart.
- Authors
Virkamaki, Antti; Yki-Jarvinen, Hannele
- Abstract
Examines the allosteric regulation of glycogen synthase and hexokinase during glucosamine-induced insulin resistance in skeletal muscle and heart. Effect of glucosamine on intracellular metabolites of the hexosamine pathway; Similarity of structure between the glucose-6-phosphate and GlcN6P; Significance of GlcN6P accumulation.
- Subjects
GLYCOGEN; ALLOSTERIC regulation; GLUCOSAMINE; INSULIN resistance
- Publication
Diabetes, 1999, Vol 48, Issue 5, p1101
- ISSN
0012-1797
- Publication type
Article
- DOI
10.2337/diabetes.48.5.1101