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- Title
Evidence that SARS-CoV-2 Induces Lung-Cell Senescence: Potential Impact on COVID-19 Lung Disease.
- Authors
Lipskaia, Larissa; Maisonnasse, Pauline; Fouillade, Charles; Sencio, Valentin; Pascal, Quentin; Flaman, Jean-Michel; Born, Emmanuelle; London-Vallejo, Arturo; Le Grand, Roger; Bernard, David; Trottein, François; Adnot, Serge
- Abstract
The article provides information on a study on the effect of SARS-CoV-2 on lung-cell senescence. Topics discussed include differential gene-expression analysis performed using model-based analysis of single-cell transcriptomics (MAST), expression of senescence markers, and histopathology and immunohistochemistry.
- Subjects
LUNG diseases; GENE expression; TRANSCRIPTOMES; IMMUNOHISTOCHEMISTRY; SARS disease
- Publication
American Journal of Respiratory Cell & Molecular Biology, 2022, Vol 66, Issue 1, pE1
- ISSN
1044-1549
- Publication type
Article
- DOI
10.1165/rcmb.2021-0205le