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- Title
SNH Amidation of 5-Nitroisoquinoline: Access to Nitro- and Nitroso Derivatives of Amides and Ureas on the Basis of Isoquinoline.
- Authors
Avakyan, Elena K.; Borovleva, Anastasia A.; Pobedinskaya, Diana Yu.; Demidov, Oleg P.; Ermolenko, Artem P.; Larin, Alexander N.; Borovlev, Ivan V.
- Abstract
For the first time, amides and ureas based on both 5-nitroisoquinoline and 5-nitrosoisoquinoline were obtained by direct nucleophilic substitution of hydrogen in the 5-nitroisoquinoline molecule. In the case of urea and monosubstituted ureas, only 5-nitrosoisoquinoline-6-amine is formed under anhydrous conditions.
- Subjects
AMIDE derivatives; AMIDATION; UREA; UREA derivatives; ISOQUINOLINE; ALKALOIDS; ISOQUINOLINE alkaloids; AMIDES
- Publication
Molecules, 2022, Vol 27, Issue 22, p7862
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules27227862