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- Title
BIOCHEMICAL STUDY AND SYNTHESIS OF NEW PHARMACEUTICALS COMPOUNDS CONTAINING PHENOXAZINE MOIETIES.
- Authors
Kadhim, Muqdad Irhaeem
- Abstract
The current study includes synthesis of new derivatives of Phenoxazine, in order to obtain these derivatives; á,â-unsaturated ketone [5] was adopted to a Aldol condensation reaction between 10-ethyl-3-phenoxazin-3-yl aldehyde, that used with some different amine such as hydrazine hydrochloride, Hydrazinobenzene, Hydrazinecarbothioamide and Nitrinous acid to give pyrazolines [6,7,8,9,10] and oxazoline[11]. All prepared compounds have been characterized by Elemental-Analysis [CHN] and other spectroscopic methods such as FT-IR, NMR and Mass fragmentation. All pyrazolines and oxazoline were treated against bacterial and fungicidal and compare with pharmaceuticals and biological activity.
- Subjects
MOIETIES (Chemistry); PHENOXAZINONE; ALDOL condensation; PYRAZOLINONES; OXAZOLINE; DRUGS
- Publication
Biochemical & Cellular Archives, 2020, Vol 20, Issue 2, p6647
- ISSN
0972-5075
- Publication type
Article