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- Title
Synthesis and evaluation of α-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interest.
- Authors
Eissa, A. M. F.; El-Sayed, R.
- Abstract
T2-Hydroxyheptadecanoic acid chloride (2) reacted with anthranilic acid to produce 2-substituted-3,1-benzoxazin-4-one (3) which was used as starting material to synthesize some condensed and non-condensed heterocyclic compounds by reaction with nitrogen nucleophiles e.g., hydrazine hydrate, and formamide. The products were subjected to reaction with different moles of propylene oxide (n = 5, 10, 15) to produce a novel group of nonionic compounds having a double function as antibacterial and surface active agents which can be used in the manufacturing of drugs, cosmetics, pesticides or can be used as antibacterial and/or antifungal additives. The surface active properties as surface and interfacial tension, cloud point, foaming height, wetting time, and emulsification power were determined, the antimicrobial and biodegradability were also screened.
- Subjects
CHLORIDES; HETEROCYCLIC compounds; HYDRATES; FORMAMIDE; PROPYLENE oxide; SURFACE active agents; ANTI-infective agents; DRUGS
- Publication
Grasas y Aceites, 2006, Vol 57, Issue 4, p367
- ISSN
0017-3495
- Publication type
Article
- DOI
10.3989/gya.2006.v57.i4.61