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Concomitant histone deacetylase and phosphodiesterase 5 inhibition synergistically prevents the disruption in synaptic plasticity and it reverses cognitive impairment in a mouse model of Alzheimer's disease.
- Published in:
- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0142-9
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- Publication type:
- Article
Analysis of the Polycomb-related lncRNAs HOTAIR and ANRIL in bladder cancer.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0141-x
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- Article
Selective increase in subtelomeric DNA methylation: an epigenetic biomarker for malignant glioma.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0140-y
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- Publication type:
- Article
Circulating nucleosomes as epigenetic biomarkers in pancreatic cancer.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0139-4
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- Publication type:
- Article
Transgelin gene is frequently downregulated by promoter DNA hypermethylation in breast cancer.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0138-5
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- Article
Analysis of DNA methylation landscape reveals the roles of DNA methylation in the regulation of drug metabolizing enzymes.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0136-7
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- Publication type:
- Article
Decreased efficacy of drugs targeting the vascular endothelial growth factor pathway by the epigenetic silencing of FLT1 in renal cancer cells.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0134-9
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- Publication type:
- Article
The placenta: phenotypic and epigenetic modifications induced by Assisted Reproductive Technologies throughout pregnancy.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0120-2
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- Article
Epigenetic control of HIV-1 post integration latency: implications for therapy.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0137-6
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- Publication type:
- Article
Global analysis of DNA methylation in hepatocellular carcinoma by a liquid hybridization capture-based bisulfite sequencing approach.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0121-1
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- Publication type:
- Article
Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0132-y
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- Publication type:
- Article
Targeted next-generation sequencing reveals high frequency of mutations in epigenetic regulators across treatment-naïve patient melanomas.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0091-3
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- Publication type:
- Article
Whole-genome bisulfite sequencing of cell-free DNA identifies signature associated with metastatic breast cancer.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0135-8
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- Publication type:
- Article
Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0133-x
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- Publication type:
- Article
Methylome profiling reveals functions and genes which are differentially methylated in serrated compared to conventional colorectal carcinoma.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0128-7
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- Publication type:
- Article
Epigenetic synergy between decitabine and platinum derivatives.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0131-z
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- Publication type:
- Article
Epidemiologic evidence for association between adverse environmental exposures in early life and epigenetic variation: a potential link to disease susceptibility?
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0130-0
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- Publication type:
- Article
Nucleated red blood cells impact DNA methylation and expression analyses of cord blood hematopoietic cells.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0129-6
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- Publication type:
- Article
High cortisol in 5-year-old children causes loss of DNA methylation in SINE retrotransposons: a possible role for ZNF263 in stress-related diseases.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0123-z
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- Publication type:
- Article
Musical patterns for comparative epigenomics.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0127-8
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- Publication type:
- Article
The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0126-9
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- Publication type:
- Article
Breast cancer risk and imprinting methylation in blood.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0125-x
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- Publication type:
- Article
Exploration of hydroxymethylation in Kagami- Ogata syndrome caused by hypermethylation of imprinting control regions.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0124-y
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- Publication type:
- Article
High cortisol in 5-year-old children causes loss of DNA methylation in SINE retrotransposons: a possible role for ZNF263 in stress-related diseases.
- Published in:
- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0123-z
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- Publication type:
- Article
Triage of high-risk human papillomavirus-positive women by methylated POU4F3.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0122-0
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- Publication type:
- Article
DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0094-0
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- Publication type:
- Article
MicroRNA expression profiling predicts clinical outcome of carboplatin/paclitaxel-based therapy in metastatic melanoma treated on the ECOG-ACRIN trial E2603.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0092-2
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- Publication type:
- Article
Detection of nasopharyngeal carcinoma in Morocco (North Africa) using a multiplex methylation-specific PCR biomarker assay.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0119-8
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- Publication type:
- Article
Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0118-9
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- Article
5-Carboxylcytosine levels are elevated in human breast cancers and gliomas.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0117-x
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- Article
Prenatal parental tobacco smoking, gene specific DNA methylation, and newborns size: the Generation R study.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0115-z
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- Publication type:
- Article
Epigenome-wide and transcriptome-wide analyses reveal gestational diabetes is associated with alterations in the human leukocyte antigen complex.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0116-y
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- Publication type:
- Article
A varying T cell subtype explains apparent tobacco smoking induced single CpG hypomethylation in whole blood.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0113-1
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- Article
DNA methylation signature of interleukin 1 receptor type II in asthma.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0114-0
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- Publication type:
- Article
Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0104-2
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- Publication type:
- Article
MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0107-z
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- Publication type:
- Article
Comparison of HPV genotyping and methylated ZNF582 as triage for women with equivocal liquid-based cytology results.
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- 2015
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- Publication type:
- Case Study
DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0112-2
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- Publication type:
- Article
Review of the development of DNA methylation as a marker of response to neoadjuvant therapy and outcomes in rectal cancer.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0111-3
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- Publication type:
- Article
Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE<sub>2</sub> in colorectal cancer.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0110-4
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- Publication type:
- Article
DNA hydroxymethylation age of human blood determined by capillary hydrophilic-interaction liquid chromatography/mass spectrometry.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0109-x
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- Publication type:
- Article
Identifying CpG sites associated with eczema via random forest screening of epigenome-scale DNA methylation.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0108-y
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- Publication type:
- Article
Different prognostic effect of CpG island methylation according to sex in colorectal cancer patients treated with adjuvant FOLFOX.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0106-0
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- Publication type:
- Article
Global DNA methylation changes and differential gene expression in Anaplasma phagocytophilum-infected human neutrophils.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0105-1
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- Publication type:
- Article
MethPed: a DNA methylation classifier tool for the identification of pediatric brain tumor subtypes.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0103-3
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- Publication type:
- Article
DNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0102-4
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- Publication type:
- Article
Recent developments on the role of epigenetics in obesity and metabolic disease.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0101-5
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- Publication type:
- Article
Colorimetric detection of both total genomic and loci-specific DNA methylation from limited DNA inputs.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0100-6
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- Publication type:
- Article
Circulating microRNA-144-5p is associated with depressive disorders.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0099-8
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- Publication type:
- Article
DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis.
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- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0098-9
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- Publication type:
- Article