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The tyrosine phosphatase Shp‐2 confers resistance to colonic inflammation by driving goblet cell function and crypt regeneration.
- Published in:
- Journal of Pathology, 2019, v. 247, n. 1, p. 135, doi. 10.1002/path.5177
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- Publication type:
- Article
Receptor-stimulated oxidation of SHP-2 promotes T-cell adhesion through SLP-76–ADAP.
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- EMBO Journal, 2005, v. 24, n. 13, p. 2331, doi. 10.1038/sj.emboj.7600706
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- Article
Tyr66 acts as a conformational switch in the closed-to-open transition of the SHP-2 N-SH2-domain phosphotyrosine-peptide binding cleft.
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- BMC Structural Biology, 2007, v. 7, p. 14, doi. 10.1186/1472-6807-7-14
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- Article
Extracellular arginine is required but the arginine transporter CAT3 (Slc7a3) is dispensable for mouse normal and malignant hematopoiesis.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-24554-2
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- Publication type:
- Article
Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner.
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- Science Signaling, 2018, v. 11, n. 522, p. 1, doi. 10.1126/scisignal.aao1591
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- Article
Activating Mutations in Protein Tyrosine Phosphatase <i>Ptpn11</i> (Shp2) Enhance Reactive Oxygen Species Production That Contributes to Myeloproliferative Disorder
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- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063152
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- Publication type:
- Article
Structural mechanism associated with domain opening in gain-of-function mutations in SHP2 phosphatase.
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- Proteins, 2011, v. 79, n. 5, p. 1573, doi. 10.1002/prot.22984
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- Publication type:
- Article
A negative role of SHP-2 tyrosine phosphatase in growth factor-dependent hematopoietic cell survival.
- Published in:
- Oncogene, 2004, v. 23, n. 20, p. 3659, doi. 10.1038/sj.onc.1207471
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- Publication type:
- Article
Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling.
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- Oncogene, 2003, v. 22, n. 38, p. 5995, doi. 10.1038/sj.onc.1206846
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- Publication type:
- Article
Deficiency of MIP/MTMR14 phosphatase induces a muscle disorder by disrupting Ca<sup>2+</sup> homeostasis.
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- Nature Cell Biology, 2009, v. 11, n. 6, p. 769, doi. 10.1038/ncb1884
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- Publication type:
- Article
Shp-2 has a positive regulatory role in ES cell differentiation and proliferation.
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- Oncogene, 1998, v. 17, n. 4, p. 433, doi. 10.1038/sj.onc.1201920
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- Publication type:
- Article
Downregulation of platelet-derived growth factor receptor-β in Shp-2 mutant fibroblast cell lines.
- Published in:
- Oncogene, 1998, v. 17, n. 4, p. 441, doi. 10.1038/sj.onc.1201988
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- Publication type:
- Article
Molecular-Targeted Therapies for Hematologic Malignancies.
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- Advances in Hematology, 2012, p. 1, doi. 10.1155/2012/606423
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- Publication type:
- Article
Molecular Targets for the Treatment of Juvenile Myelomonocytic Leukemia.
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- Advances in Hematology, 2012, p. 1, doi. 10.1155/2012/308252
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- Publication type:
- Article
Factor XII and uPAR upregulate neutrophil functions to influence wound healing.
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- 2018
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- Publication type:
- journal article
Deficiency of MTMR14 promotes autophagy and proliferation of mouse embryonic fibroblasts.
- Published in:
- Molecular & Cellular Biochemistry, 2014, v. 392, n. 1/2, p. 31, doi. 10.1007/s11010-014-2015-5
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- Publication type:
- Article
Loss of Ptpmt1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure in tissue-specific knockout mice.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.86944
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- Publication type:
- Article
SHP2 as a primordial epigenetic enzyme expunges histone H3 pTyr-54 to amend androgen receptor homeostasis.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49978-4
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- Publication type:
- Article
Rapid induction and activation of Tec tyrosine kinase in liver regeneration.
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- Journal of Gastroenterology & Hepatology, 2006, v. 21, n. 4, p. 668, doi. 10.1111/j.1440-1746.2006.04259.x
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- Publication type:
- Article
AMPK activator-treated human cardiac spheres enhance maturation and enable pathological modeling.
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- Stem Cell Research & Therapy, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s13287-023-03554-7
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- Publication type:
- Article