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- Title
Plasma xanthine oxidoreductase activity change over 12 months independently associated with change in serum uric acid level: MedCity21 health examination registry.
- Authors
Kurajoh, Masafumi; Fukumoto, Shinya; Murase, Takayo; Nakamura, Takashi; Nagata, Yuki; Nakatani, Shinya; Tsuda, Akihiro; Yamada, Shinsuke; Morioka, Tomoaki; Mori, Katsuhito; Imanishi, Yasuo; Kawada, Norifumi; Hirata, Kazuto; Emoto, Masanori
- Abstract
To the Editor, Plasma xanthine oxidoreductase (XOR) activity assays previously developed are generally based on the rate of production of uric acid from its substrate xanthine, determined with an ultraviolet (UV) detector [[1]] or liquid chromatography (LC)/UV [[2]], though results obtained with those modalities are influenced by the original uric acid level. The lower limit of plasma XOR activity detection was 6.67 pmol/h/mL, while the intra- and inter-assay coefficients of variation of plasma XOR activity were 6.5 and 9.1%, respectively [[3]].
- Subjects
URIC acid; PERIODIC health examinations; ASPARTATE aminotransferase; XANTHINE
- Publication
Clinical Chemistry & Laboratory Medicine, 2021, Vol 59, Issue 4, pe137
- ISSN
1434-6621
- Publication type
Letter
- DOI
10.1515/cclm-2020-0563