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- Title
In vivo diffusion weighted <sup>19</sup>F MRI using SF<sub>6</sub>.
- Authors
Pérez-Sánchez, José M.; de Alejo, Rigoberto Pérez; Rodríguez, Ignacio; Cortijo, Manuel; Peces-Barba, Germán; Ruiz-Cabello, Jesús
- Abstract
Diffusion weighted 19F images of rat lung in vivo using SF6 are presented. Projection-reconstruction images were acquired by filling the rat lung with a mixture of SF6 and air, during 64 successive apneas. Each apnea lasted for 6 s, the time required to perform 100 accumulations of each k-space radial phase step for the five values of the diffusion gradient (TR = 10 ms). After diffusion images were acquired, an apparent diffusion coefficient (ADC) map was generated, yielding an average value for the ADC of 2.22 × 10-6 m2/s and SD for ADC values of 1.27 × 10-6 m2/s. To the best of our knowledge, this is the first in vivo diffusion weighting imaging application and the first ADC map obtained using 19F MRI. Magn Reson Med 54:460-463, 2005. © 2005 Wiley-Liss, Inc.
- Publication
Magnetic Resonance in Medicine, 2005, Vol 54, Issue 2, p460
- ISSN
0740-3194
- Publication type
Article
- DOI
10.1002/mrm.20569