We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Breathlessness and COVID-19: A Call for Research.
- Authors
Hentsch, Lisa; Cocetta, Sara; Allali, Gilles; Santana, Isabelle; Eason, Rowena; Adam, Emily; Janssens, Jean-Paul
- Abstract
Breathlessness, also known as dyspnoea, is a debilitating and frequent symptom. Several reports have highlighted the lack of dyspnoea in a subgroup of patients suffering from COVID-19, sometimes referred to as "silent" or "happy hyp-oxaemia." Reports have also mentioned the absence of a clear relationship between the clinical severity of the disease and levels of breathlessness reported by patients. The cerebral complications of COVID-19 have been largely demonstrated with a high prevalence of an acute encephalopathy that could possibly affect the processing of afferent signals or top-down modulation of breathlessness signals. In this review, we aim to highlight the mechanisms involved in breathlessness and summarize the pathophysiology of COVID-19 and its known effects on the brain-lung interaction. We then offer hypotheses for the alteration of breathlessness perception in COVID-19 patients and suggest ways of further researching this phenomenon.
- Subjects
BRAIN; COVID-19; BRAIN diseases; LUNGS; DYSPNEA; PATIENTS' attitudes; RISK assessment; COMMUNICATION; MEDICAL research; ACUTE diseases
- Publication
Respiration, 2021, Vol 100, Issue 10, p1016
- ISSN
0025-7931
- Publication type
Article
- DOI
10.1159/000517400