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- Title
Contact allergy in children with and without atopic dermatitis: An Italian multicentre study.
- Authors
Bonamonte, Domenico; Hansel, Katharina; Romita, Paolo; Fortina, Anna Belloni; Girolomoni, Giampiero; Fabbrocini, Gabriella; Patruno, Cataldo; Napolitano, Maddalena; Patrizi, Annalisa; Argenziano, Giuseppe; Micali, Giuseppe; Calzavara Pinton, Piergiacomo; Foti, Caterina; Stingeni, Luca; Barlusconi, Chiara; Bellinato, Francesco; Caccavale, Stefano; Calabrese, Giulia; Caroppo, Francesca; De Marco, Aurora
- Abstract
Background: Contact allergy and atopic dermatitis (AD) are both common inflammatory T cell‐mediated diseases and many factors may influence the prevalence of contact allergy in AD patients. In children, their possible correlation was debated with conflicting results. Objectives: The present study aimed to assess the prevalence of contact sensitivity in children and to investigate the association with AD. Materials and methods: A retrospective multicentre study on children aged from 0 to 14 years patch tested between January 2017 and December 2018 was performed. Children were consecutively patch tested with the SIDAPA (Società Italiana Dermatologia Allergologica Professionale Ambientale) baseline series. Results: Among the 432 children investigated for contact allergy, 125 (28.9%) showed a positive reaction to at least one of the allergens tested, with a higher prevalence of positive patch test reactions in girls (32.3%) than in boys (25.0%). The most frequent contact allergens were nickel sulphate (10.2%), cobalt chloride (6.7%), methylisothiazolinone (3.7%), fragrance mix‐2 (3.2%), potassium dichromate (2.8%), fragrance mix‐1 (2.1%) and methylchloroisothiazolinone/methylisothiazolinone (2.1%). One‐hundred‐three children (23.8%) suffered from AD showing a higher prevalence of positive patch test (36.9%) compared to children without AD (26.4%). Conclusions: Despite the topic being still controversial, the present study suggests a consistent prevalence of contact allergy among children with higher sensitivity rate among children with AD than without AD.
- Subjects
ATOPIC dermatitis; NICKEL sulfate; ALLERGIES; CONTACT dermatitis; COBALT chloride; ECZEMA; MILK allergy
- Publication
Contact Dermatitis (01051873), 2022, Vol 87, Issue 3, p265
- ISSN
0105-1873
- Publication type
Article
- DOI
10.1111/cod.14130