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- Title
Compared Localizations of Prolactin-Like and Adrenocorticotropin Immunoreactivities within the Brain of the Rat.
- Authors
Toubeau, G.; Desclin, J.; Parmentier, M.; Pasteels, J.L.
- Abstract
By an immunoperoxidase (PAP) technique, ACTH- and prolactin-like substances were detected in neurons of several hypothalamic nuclei in young and adult rats. Neurons in the arcuate and ventromedial nuclei were simultaneously both ACTH-like and PRL-like positive. Labelled fibres were followed to their fields of projections. Intensity of labelling was not influenced by experimental procedures known to change PRL and ACTH content of the pituitary. Colchicine enhanced labelling of perikarya while lowering that of fibres. The results support neuronal synthesis of hormonal ACTH and PRL related molecules and their involvement in the control of autonomic nerve functions. Copyright © 1979 S. Karger AG, Basel
- Publication
Neuroendocrinology, 1979, Vol 29, Issue 6, p374
- ISSN
0028-3835
- Publication type
Article
- DOI
10.1159/000122948