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- Title
Prebiotic Effects of Chinese Herbal Polysaccharides on NAFLD Amelioration: The Preclinical Progress.
- Authors
Jiang, Li-Yan; Kan, Yu-Na; Yu, Zhi-Pu; Jian, Bai-Yu; Yao, Shu-Juan; Lv, Li-Yan; Liu, Ji-Cheng
- Abstract
Nonalcoholic fatty liver disease (NAFLD) is caused by fatty degeneration of liver cells, and there are currently no effective treatments. Numerous investigations have demonstrated that Chinese herbal medicines (CHMs) are effective against NAFLD. Polysaccharides (PS), the major components of most CHM, are primarily taken orally to be degraded and fermented by gut microbiota, which makes them a promising multivalent and multifunctional prebiotic candidate for NAFLD. In this review, the experimental evidence to prevent and treat NAFLD using the unique prebiotic effects of PS isolated from CHM are summarized to discuss additional treatment options for NAFLD.
- Subjects
NON-alcoholic fatty liver disease; FATTY degeneration; POLYSACCHARIDES; FRUCTOOLIGOSACCHARIDES; INULIN; LIVER cells; GUT microbiome
- Publication
Natural Product Communications, 2022, Vol 17, Issue 11, p1
- ISSN
1934-578X
- Publication type
Article
- DOI
10.1177/1934578X221124751