We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Toxicities of Neonicotinoid‐Containing Pesticide Mixtures on Nontarget Organisms.
- Authors
Zhao, Guo‐Ping; Yang, Fang‐Wei; Li, Jin‐Wang; Xing, Han‐Zhu; Ren, Fa‐Zheng; Pang, Guo‐Fang; Li, Yi‐Xuan
- Abstract
Neonicotinoids are a widely used class of pesticides. Co‐exposure to neonicotinoids and other classes of pesticides can exert potentiating or synergistic effects, and these mixtures have been detected in human bodily fluids. The present review summarizes studies into the effects of neonicotinoid‐containing pesticide mixtures on humans and other nontarget organisms. Exposure to these mixtures has been reported to result in reproductive and hormonal toxicity, genotoxicity, neurotoxicity, hepatotoxicity, and immunotoxicity in vertebrates. Mortality of pollinators and toxicity in other organisms has also been reported. The underlying mechanism of pesticide mixture toxicity may be associated with impairment of cytochrome 450 enzymes, which are involved in metabolizing pesticides. However, a comprehensive explanation of the adverse effects of neonicotinoid‐containing pesticide mixtures is still required so that effective prevention and control measures can be formulated. Environ Toxicol Chem 2020;39:1884–1893. © 2020 SETAC
- Subjects
PESTICIDES; MIXTURES; NEONICOTINOIDS; GENETIC toxicology; IMMUNOTOXICOLOGY; NEUROTOXICOLOGY; INSECTICIDES
- Publication
Environmental Toxicology & Chemistry, 2020, Vol 39, Issue 10, p1884
- ISSN
0730-7268
- Publication type
Article
- DOI
10.1002/etc.4842