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- Title
Laboratory assessments in the course of Parkinson's disease: a clinician's perspective.
- Authors
Müller, Thomas; Baas, Horst; Kassubek, Jan; Riederer, Peter; Urban, Peter; Schrader, Christoph; Reichmann, Heinz; Woitalla, Dirk; Gerlach, Manfred
- Abstract
Physicians, caregivers and patients themselves must be alert to the onset of and changes in motor and non-motor features during the course of Parkinson's disease (PD). Parallel laboratory routine assessments are necessary because of the evolving impairment of the general health status of the individual. A number of potential biomarkers for the diagnosis of PD are currently under investigation, with diagnosis early in the disease course a particular goal, even before the onset of motor symptoms. The aim of this guideline article is to provide user-friendly, clinical evidence-based recommendations for using laboratory pathological testing for the diagnosis and differential diagnosis of PD, for assessing its time course, and managing complications of long-term dopaminergic therapy and the disabling motor features that develop in the later stages of the disease.
- Subjects
PARKINSON'S disease; LACTATION consultants; BIOMARKERS; MOTOR ability; DOPAMINERGIC neurons
- Publication
Journal of Neural Transmission, 2016, Vol 123, Issue 1, p65
- ISSN
0300-9564
- Publication type
Article
- DOI
10.1007/s00702-015-1481-6