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- Title
Sympathetic skin response and R-R interval variation in chronic uremic patients.
- Authors
Wang, Shuu-Jiun; Liao, Kwong-Kum; Liou, Hung-Hsiang; Lee, Shei-Shee; Tsai, Ching-Piao; Lin, Kon-Ping; Kao, Ko-Pei; Wu, Zin-An
- Abstract
Sympathetic skin response (SSR) and R-R interval variation (RRIV) were studied in 36 chronic, nondiabetic uremics to compare with their nerve conduction studies (NCS) and clinical dysautonomia. Abnormal SSR was noted in 5 (13.9%) patients, abnormal RRIV in 14 (38.9%), and abnormal NCS in 26 (72.2%). The patients were classified into three groups: group (GP) 1: 'normal,' n = 21 (58.3%), normal RRIV and SSR; GP 2: 'isolated parasympathetic dysfunction,' n = 10 (27.8%), abnormal RRIV and normal SSR; and GP 3: 'sympathetic sudomotor dysfunction,' n = 5 (13.9%), abnormal SSR. A significant difference in age was found among the three groups (GP 3 > GP 2 > GP 1; P < 0.0001, ANOVA). After controlling the age factor, we still noted a tendency toward increasing NCS disturbances (distal latency and nerve conduction velocity of peroneal nerve; P < 0.05, multiple regression analysis) and frequencies of clinical autonomic symptoms (postural dizziness and impotence; P < 0.05, Mantel-Hanszel test) from GP 1 to GP 3. Patients with abnormal SSR (GP 3) displayed significantly higher frequencies of postural dizziness and impotence, indicating the relationship between an absence of SSR and clinical dysautonomia. © 1994 John Wiley & Sons, Inc.
- Publication
Muscle & Nerve, 1994, Vol 17, Issue 4, p411
- ISSN
0148-639X
- Publication type
Article
- DOI
10.1002/mus.880170408