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- Title
Edrophonium responsiveness not necessarily diagnostic of myasthenia gravis.
- Authors
Oh, Shin J.; Cho, Hyo K.
- Abstract
Uneqivocally positive edrophonium tests, both clinically and electrophysiologically, were observed in a classic case of the Lambert-Eaton myasthenic syndrome. A review of the literature revealed that a positive edrophonium response has been reported in a majority of cases of myasthenia gravis (MG) and overlap myasthenic syndrome and in some cases of the Lambert-Eaton myasthenic syndrome, botulism, congenital myasthenic syndrome, drug-induced myasthenic syndrome, the Guillain-Barre syndrome, and amyotrophic lateral sclerosis. From this, we conclude that anunequivocally positive edrophonium test alone is not necessarily diagnostic of MG and that the diagnosis of MG should be based on the clinical features together with edrophonium-responsiveness and other laboratory findings.
- Publication
Muscle & Nerve, 1990, Vol 13, Issue 3, p187
- ISSN
0148-639X
- Publication type
Article
- DOI
10.1002/mus.880130302