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- Title
Oral cavity and oropharyngeal cancer in a younger population. Review of literature and experience at Yale.
- Authors
Son, Yung H.; Kapp, Daniel S.; Son, Y H; Kapp, D S
- Abstract
Oral cavity and oropharyngeal cancer in younger adults is a rare entity with an incidence of 2.7% among 1014 patients seen or treated at the Department of Therapeutic Radiology, Yale - New Haven Medical Center between 1958 and 1980. Although there are reports of contrastingly divergent therapeutic experiences, the authors contend that even early stage cancers frequently fail definitive therapy with a rampant course, causing a rapidly fatal outcome. The three-year actuarial survival was a mere 17% at Yale. The authors speculate that younger adult oral cavity and oropharyngeal cancers are possibly related to a genetic disorder or immunodeficiency, and recommend aggressive surgical and radiotherapeutic approaches combined with possible adjuvant immunotherapy.
- Publication
Cancer (0008543X), 1985, Vol 55, Issue 2, p441
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19850115)55:2<441::AID-CNCR2820550225>3.0.CO;2-5