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- Title
RNA N6-methyladenosine: a new player in autophagy-mediated anti-cancer drug resistance.
- Authors
Paramasivam, Arumugam; Priyadharsini, Jayaseelan Vijayashree
- Abstract
Dysregulation of N6-methyladenosine (m6A) modification is associated with cancer development and progression. The m6A modification plays a crucial role in autophagy regulation precipitating anti-cancer drug resistance. In line with this fact, this commentary discusses m6A modification interfering with autophagy machinery as a major contributing factor for drug resistance in cancer.
- Publication
British Journal of Cancer, 2021, Vol 124, Issue 10, p1621
- ISSN
0007-0920
- Publication type
journal article
- DOI
10.1038/s41416-021-01314-z