We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Long-term clinical outcomes after single freeze cryoballoon ablation for paroxysmal atrial fibrillation: a 5-year follow-up.
- Authors
Mugnai, Giacomo; Paparella, Gaetano; Overeinder, Ingrid; Ströker, Erwin; Sieira, Juan; Bisignani, Antonio; Iacopino, Saverio; Boveda, Serge; Beckers, Stefan; Umbrain, Vincent; Bala, Gezim; Brugada, Pedro; de Asmundis, Carlo; Chierchia, Gian-Battista
- Abstract
<bold>Background: </bold>The second-generation cryoballoon ablation (CB-A) has been proven to be safe and effective for pulmonary vein (PV) isolation. Little is known regarding the long-term outcome following CB-A ablation for paroxysmal atrial fibrillation (AF). The aim of the study was to evaluate the freedom from atrial arrhythmias during a 5-year follow-up period among consecutive patients having undergone PV isolation with the CB-A for paroxysmal AF METHODS AND RESULTS: A total of 208 consecutive patients having undergone index PV isolation using CB-A (138 males, 66%; mean age 59.0 ± 12.6 years) were included in our retrospective analysis. Follow-up was based on outpatient clinic visits including Holter electrocardiograms. Recurrence of atrial tachyarrhythmias was defined as a symptomatic or documented episode of > 30 s. At a median follow-up of 62 months, freedom from atrial arrhythmias after a single procedure was achieved in 57.2% of patients. Multivariate analysis demonstrated that obesity, left atrial diameter, and duration of symptoms before AF ablation were independent predictors of ATas recurrences. Major complications occurred in 2.4% of patients.<bold>Conclusions: </bold>The present study found a 5-year single-procedure success rate of 57.2% following CB-A ablation procedure. Obesity, higher LA dimensions, and longer duration of symptoms before ablation independently predicted the outcome.
- Subjects
ATRIAL fibrillation; ATRIAL arrhythmias; TREATMENT effectiveness; PULMONARY veins; SYMPTOMS; OBESITY
- Publication
Journal of Interventional Cardiac Electrophysiology, 2021, Vol 61, Issue 1, p87
- ISSN
1383-875X
- Publication type
journal article
- DOI
10.1007/s10840-020-00788-w