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- Title
Effective motion-sensitizing magnetization preparation for black blood magnetic resonance imaging of the heart.
- Authors
Nguyen, Thanh D.; de Rochefort, Ludovic; Spincemaille, Pascal; Cham, Matthew D.; Weinsaft, Jonathan W.; Prince, Martin R.; Wang, Yi
- Abstract
Purpose To investigate the effectiveness of flow signal suppression of a motion-sensitizing magnetization preparation (MSPREP) sequence and to optimize a 2D MSPREP steady-state free precession (SSFP) sequence for black blood imaging of the heart. Materials and Methods Using a flow phantom, the effect of varying field of speed (FOS), b-value, voxel size, and flow pattern on the flow suppression was investigated. In seven healthy volunteers, black blood images of the heart were obtained at 1.5T with MSPREP-SSFP and double inversion recovery fast spin echo (DIR-FSE) techniques. Myocardium and blood signal-to-noise ratio (SNR) and myocardium-to-blood contrast-to-noise ratio (CNR) were measured. The optimal FOS that maximized the CNR for MSPREP-SSFP was determined. Results Phantom data demonstrated that the flow suppression was induced primarily by the velocity encoding effect. In humans, FOS = 10-20 cm/s was found to maximize the CNR for short-axis (SA) and four-chamber (4C) views. Compared to DIR-FSE, MSPREP-SSFP provided similar blood SNR efficiency in the SA basal and mid-views and significantly lower blood SNR efficiency in the SA apical ( P = 0.02) and 4C ( P = 0.01) views, indicating similar or better blood suppression. Conclusion Velocity encoding is the primary flow suppression mechanism of the MSPREP sequence and 2D MSPREP-SSFP black blood imaging of the heart is feasible in healthy subjects. J. Magn. Reson. Imaging 2008;28:1092-1100. © 2008 Wiley-Liss, Inc.
- Publication
Journal of Magnetic Resonance Imaging, 2008, Vol 28, Issue 5, p1092
- ISSN
1053-1807
- Publication type
Article
- DOI
10.1002/jmri.21568