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- Title
Evaluation of Hepatitis B Serology After Primary Immunization in Babies of Hepatitis B Carrier Mothers.
- Authors
ÖZEREN, Öykü Zeren; ÇALI ÖZTÜRK, Halime; BAKAR, Rabia Zehra; ÇETİN, Çağlar; TORUN, Emel
- Abstract
Introduction: Hepatitis is an inflammatory condition of the liver caused by hepatitis B virus. In our country, infants of hepatitis B carrier mothers are vaccinated and administered immunoglobulin at birth. In addition, the infants are vaccinated again when they are 1 and 6 months old. In serologic evaluations, HBsAg positivity indicates carriage. Hepatitis B antibodies in IgG and IgM structures show immunization. In Turkey, after the vaccines are administered, immunization is evaluated with hepatitis B antibody when the infants are 9 and 15 months old. In studies evaluating hepatitis B serology, gestational week, gender, duration of breastfeeding, type of delivery, and birth weight are rarely considered. We contribute to the elucidation of the effect of these characteristics in our study. Method: Infants of hepatitis B carrier mothers who presented to Bezmialem Vakıf University Medical Faculty Hospital Pediatrics and Obstetrics & Gynecology Polyclinics were included in the study. The data, including the infants' immunization status, gender, gestational weeks, type of birth, birth weight, and duration of breast milk intake, were collected from the hospital database of previously followed-up patients in the presence of a physician. The effect of these criteria on immune response formation was evaluated. Results: Of the 166 patients evaluated, 50.6% were male (group 1), 27.7% preterm (group 2), 7.8% had low birth weight (group 3), 40% were a cesarean delivery baby (group 4), 26.5% breastfed for less than 6 months (group 5), and these characteristics did not affect immune response (p values were group 1, p=0.680; group 2, p=1; group 3, p=1; group 4, p=0.234; group 5, p=1). Conclusion: Infant gender, gestational week, birth weight, mode of delivery, and duration of breastfeeding did not affect immunity developed by the hepatitis B vaccine.
- Subjects
TURKEY; HEPATITIS B; LOW birth weight; DELIVERY (Obstetrics); HEPATITIS B vaccines; IMMUNIZATION
- Publication
Bezmialem Science, 2024, Vol 13, pS45
- ISSN
2148-2373
- Publication type
Article