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- Title
Effects of Bundle Treatment on Myocardial injury and Hemodynamics of Macaca rhesus with Septic shock.
- Authors
WANG Xiao; YANG De-xing; LI Xue-jiao; XIA Jing; QIAN Chuan-yun
- Abstract
Objective To investigate the significance of bundle treatment in myocardial structure injury and hemodynamic changes on macaca rhesus with septic shock. Methods We divided 12 macaca rhesus with septic shock into two groups randomly, 6 in each group, and randomly selected a group as a control group, the other group as the experimental group.The control group was only given basic life support, experimental group was given bundle treatment, then we tested the MAP before starting treatment and after treatment for first hour, second hour, third hour, fourth hour, fifth hour and sixth hour, and tested the CVP, PAWP, CI, SVR, PVR, LVWI and RWI for six hours after treatment. Results The CVP, CI, RWI for six hours after treatment had statistical difference (P< 0.05) ; the levels of myocardial structure injury, PAWP, SVR, PVR, LVWI had no statistical difference, (P> 0.05) , in repeated measures ANOVA: MAP within group comparison test: in different course had no statistical difference (P = 0.06) , the interaction of drugs and course had no statistic difference (P = 0.23) and effect test between two groups had statistic difference (P< 0.01) . Conclusion Bundle treatment for six hours can stop the macaca rhesus septic shock, but has no protective effects on myocardial cell of macaca rhesus septic shock.
- Publication
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao, 2014, Vol 35, Issue 4, p10
- ISSN
2095-610X
- Publication type
Article