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Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds.
Published in:
2009
By:
- Yan Feng;
- Mitchison, Timothy J.;
- Bender, Andreas;
- Young, Daniel W.;
- Tallarico, John A.;
- Feng, Yan
Publication type:
journal article
Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.17290
By:
- DeJesus, Rowena;
- Moretti, Francesca;
- McAllister, Gregory;
- Zuncai Wang;
- Bergman, Phil;
- Shanming Liu;
- Frias, Elizabeth;
- Alford, John;
- Reece-Hoyes, John S.;
- Lindeman, Alicia;
- Kelliher, Jennifer;
- Russ, Carsten;
- Knehr, Judith;
- Carbone, Walter;
- Beibel, Martin;
- Roma, Guglielmo;
- Ng, Aylwin;
- Tallarico, John A.;
- Porter, Jeffery A.;
- Xavier, Ramnik J.
Publication type:
Article
Discovery of Potent Pyrazoline‐Based Covalent SARS‐CoV‐2 Main Protease Inhibitors.
Published in:
ChemBioChem, 2023, v. 24, n. 11, p. 1, doi. 10.1002/cbic.202300116
By:
- Moon, Patrick;
- Zammit, Charlotte M.;
- Shao, Qian;
- Dovala, Dustin;
- Boike, Lydia;
- Henning, Nathaniel J.;
- Knapp, Mark;
- Spradlin, Jessica N.;
- Ward, Carl C.;
- Wolleb, Helene;
- Fuller, Daniel;
- Blake, Gabrielle;
- Murphy, Jason P.;
- Wang, Feng;
- Lu, Yipin;
- Moquin, Stephanie A.;
- Tandeske, Laura;
- Hesse, Matthew J.;
- McKenna, Jeffrey M.;
- Tallarico, John A.
Publication type:
Article
Bardoxolone conjugation enables targeted protein degradation of BRD4.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72491-9
By:
- Tong, Bingqi;
- Luo, Mai;
- Xie, Yi;
- Spradlin, Jessica N.;
- Tallarico, John A.;
- McKenna, Jeffrey M.;
- Schirle, Markus;
- Maimone, Thomas J.;
- Nomura, Daniel K.
Publication type:
Article
DNA sequencing and CRISPR-Cas9 gene editing for target validation in mammalian cells.
Published in:
Nature Chemical Biology, 2014, v. 10, n. 8, p. 623, doi. 10.1038/nchembio.1550
By:
- Smurnyy, Yegor;
- Cai, Mi;
- Wu, Hua;
- McWhinnie, Elizabeth;
- Tallarico, John A;
- Yang, Yi;
- Feng, Yan
Publication type:
Article
Natural products reveal cancer cell dependence on oxysterol-binding proteins.
Published in:
Nature Chemical Biology, 2011, v. 7, n. 9, p. 639, doi. 10.1038/nchembio.625
By:
- Burgett, Anthony W G;
- Poulsen, Thomas B;
- Wangkanont, Kittikhun;
- Anderson, D Ryan;
- Kikuchi, Chikako;
- Shimada, Kousei;
- Okubo, Shuichi;
- Fortner, Kevin C;
- Mimaki, Yoshihiro;
- Kuroda, Minpei;
- Murphy, Jason P;
- Schwalb, David J;
- Petrella, Eugene C;
- Cornella-Taracido, Ivan;
- Schirle, Markus;
- Tallarico, John A;
- Shair, Matthew D
Publication type:
Article
Integrating high-content screening and ligand-target prediction to identify mechanism of action.
Published in:
Nature Chemical Biology, 2008, v. 4, n. 1, p. 59, doi. 10.1038/nchembio.2007.53
By:
- Young, Daniel W;
- Bender, Andreas;
- Hoyt, Jonathan;
- McWhinnie, Elizabeth;
- Gung-Wei Chirn;
- Tao, Charles Y;
- Tallarico, John A;
- Labow, Mark;
- Jenkins, Jeremy L;
- Mitchison, Timothy J;
- Yan Feng
Publication type:
Article
Small molecules that delay S phase suppress a zebrafish bmyb mutant.
Published in:
Nature Chemical Biology, 2005, v. 1, n. 7, p. 366, doi. 10.1038/nchembio749
By:
- Stern, Howard M.;
- Murphey, Ryan D.;
- Shepard, Jennifer L.;
- Amatruda, James F.;
- Straub, Christian T.;
- Pfaff, Kathleen L.;
- Weber, Gerhard;
- Tallarico, John A.;
- King, Randall W.;
- Zon, Leonard I.
Publication type:
Article

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