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- Title
An unusual case of aggressive malignant spread of epithelioid hemangioendothelioma.
- Authors
Hickman, Ashley D; Bezerra, Evandro D; Roden, Anja C; Houdek, Matthew T; Barlow, Jonathan D; Robinson, Steven I; Wahner Hendrickson, Andrea E
- Abstract
Epithelioid hemangioendothelioma (EHE) is a rare vascular neoplasm which typically originates from liver, lung, or bone. Due to the low incidence of disease, the most effective treatment is not easily studied and much of the information known about EHE has been learned through case reports and case series. In this case, we will present an uncommon form of primary soft tissue EHE with local recurrence, bone metastasis, and lymphangitic spread to the lungs leading to respiratory failure. Imaging of the chest was atypical for EHE with intraseptal thickening and hilar lymphadenopathy. Respiratory failure was progressive despite aggressive multimodal treatment. This case highlights an unusually aggressive recurrence and metastasis of primary soft tissue EHE with atypical pulmonary imaging findings.
- Subjects
RESPIRATORY insufficiency; BONE metastasis; CANCER relapse; COMBINED modality therapy; DISEASE incidence; CELL tumors
- Publication
Rare Tumors, 2021, p1
- ISSN
2036-3605
- Publication type
Case Study
- DOI
10.1177/20363613211010858