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- Title
Giant Cell Carcinoma of the Hypopharynx: Pathologic Diagnosis and Natural History.
- Authors
Heathcote, J. Godfrey; Matthews, T. Wayne; Tsang, Wendy
- Abstract
The article reports a case of giant cell carcinoma of the hypopbarynx treated with chemoradiation and salvage laryngopharyngectomy and associated with fatal metastatic disease. A 48-year-old man presented in February 2000 with dysphagia, odynophagia, and hoarseness of 3 months duration. Indirect laryngoscopy revealed a large, exophytic mass arising in the right hypopharynx. Vocal cord mobility was unimpaired, and there was no lymphadenopathy. Examination under anesthesia demonstrated a necrotic, pedunculated tumour arising from the lateral portion of the right piriform apex. Sarcomatoid carcinomas of the lung form a group of poorly differentiated neoplasms composed of atypical spindle cells and/or giant cells, often associated with elements of conventional adenocarcinoma or squamous cell carcinoma.
- Subjects
CANCER; RADIATION carcinogenesis; DEGLUTITION disorders; LARYNGOSCOPY; LARYNX examination; ANESTHESIA; ADENOCARCINOMA
- Publication
Journal of Otolaryngology, 2004, Vol 33, Issue 5, p322
- ISSN
0381-6605
- Publication type
Report
- DOI
10.2310/7070.2004.03017