We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Comparison Between a Manual Squamous Cell Carcinoma Antigen Assay and an Automated Assay in a Clinical Setting.
- Authors
Lee, Saejin; Kim, Juwon; Uh, Young; Kim, Hyon-Suk; Lee, Jong-Han
- Abstract
Objective To compare a manual squamous cell carcinoma antigen (SCCA) assay and an automated SCCA assay in a clinical setting. Methods We included, in this study, a total of 158 specimens that had been tested using the manual SCCA assay. The CanAg SCC EIA assay and the Elecsys SCC were compared for their clinical settings. Results Within-run and between-day coefficients of variation (CVs, %) were lower than 3%. Comparison of the manual and automated SCCA assays yielded good correlation. The correlation coefficient (R 2) between the CanAg SCC EIA and Elecsys SCC assay results was 0.989 (P <.001) and the overall concordance rate was 94.3%. Conclusions We report that the Elecsys SCC automated SCCA assay yielded performance comparable to that of the manual SCCA assay: the automated assay reduced the number of manual steps and test turnaround time.
- Subjects
BIOLOGICAL assay; CONFIDENCE intervals; REGRESSION analysis; SQUAMOUS cell carcinoma; PREDICTIVE tests; RESEARCH methodology evaluation; DATA analysis software
- Publication
Laboratory Medicine, 2018, Vol 49, Issue 3, p254
- ISSN
0007-5027
- Publication type
Article
- DOI
10.1093/labmed/lmy003