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- Title
Absence of platelet response after eradication of Helicobacter pylori infection in patients with chronic idiopathic thrombocytopenic purpura.
- Authors
Jarque, I.; Andreu, R.; Llopis, I.; De la Rubia, J.; Gomis, F.; Senent, L.; Jiménez, C.; Martín, G.; Martínez, J. A.; Sanz, G. F.; Ponce, J.; Sanz, M. A.
- Abstract
Eradication of Helicobacter pylori infection has been associated with the correction of thrombocytopenia in patients with idiopathic thrombocytopenic purpura (ITP). We have analysed the response to eradication of H. pylori in a series of 56 adult patients with chronic ITP. Forty patients had H. pylori infection (71%) that was eradicated in 23 of 32 evaluable patients (72%). Platelet counts did not significantly vary according to H. pylori treatment outcome. Three of 56 patients (5%) achieved a partial response attributable to H. pylori eradication. Therefore, detection of H. pylori infection should not be routinely included in the initial work-up of ITP.
- Subjects
BLOOD platelets; HELICOBACTER pylori infections; THROMBOCYTOPENIA
- Publication
British Journal of Haematology, 2001, Vol 115, Issue 4, p1002
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1046/j.1365-2141.2001.03194.x