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Synthesis and preliminary evaluation of 2-arylhydroxyquinoline derivatives for tau imaging.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 2014, v. 57, n. 1, p. 18, doi. 10.1002/jlcr.3133
- By:
- Publication type:
- Article
Brain histamine H<sub>1</sub> receptor occupancy after oral administration of desloratadine and loratadine.
- Published in:
- Pharmacology Research & Perspectives, 2019, v. 7, n. 4, p. N.PAG, doi. 10.1002/prp2.499
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- Publication type:
- Article
In vivo Detection of Amyloid Plaques in the Mouse Brain using the Near-Infrared Fluorescence Probe THK-265.
- Published in:
- Journal of Alzheimer's Disease, 2011, v. 23, n. 1, p. 37, doi. 10.3233/JAD-2010-100270
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- Publication type:
- Article
<sup>18</sup>F-THK5351 Positron Emission Tomography Imaging in Neurodegenerative Tauopathies.
- Published in:
- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.761010
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- Publication type:
- Article
Validation of A Novel MAO‐B PET tracer [<sup>18</sup>F]SMBT‐1 on postmortem human brain samples.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077219
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- Publication type:
- Article
Development of [<sup>18</sup>F]SNFT‐1, a novel tau PET tracer with little off‐target binding: Neuroimaging / New imaging methods.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042298
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- Publication type:
- Article
Evaluation of the novel <sup>18</sup>F‐labeled PET tracer SMBT‐1 for imaging astrogliosis in healthy elderly controls and A+/T+/(N+) Alzheimer's disease patients: Neuroimaging: Novel imaging methods.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.039858
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- Publication type:
- Article
P2‐384: DEVELOPMENT OF A NOVEL <sup>18</sup>F‐LABELED PET TRACER FOR IMAGING ASTROGLIOSIS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P750, doi. 10.1016/j.jalz.2019.06.2791
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- Publication type:
- Article
IC‐P‐141: DEVELOPMENT OF A NOVEL <sup>18</sup>F‐LABELED PET TRACER FOR IMAGING ASTROGLIOSIS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P115, doi. 10.1016/j.jalz.2019.06.4255
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- Publication type:
- Article
IC‐P‐141: DEVELOPMENT OF A NOVEL <sup>18</sup>F‐LABELED PET TRACER FOR IMAGING ASTROGLIOSIS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P115, doi. 10.1016/j.jalz.2019.06.4255
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- Publication type:
- Article
P2‐379: POTENTIAL APPLICATION OF 18F‐THK5351 AND ITS DERIVATIVES FOR IMAGING ASTROGLIOSIS IN HUMAN BRAIN.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P842, doi. 10.1016/j.jalz.2018.06.1070
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- Publication type:
- Article
IC‐P‐223: TO TAU OR TO MAO‐B? MOST OF THE [F‐18]‐THK5351 SIGNAL IS BLOCKED BY SELEGILINE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P181, doi. 10.1016/j.jalz.2018.06.2290
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- Publication type:
- Article
IC‐P‐185: POTENTIAL APPLICATION OF 18F‐THK5351 AND ITS DERIVATIVES FOR IMAGING ASTROGLIOSIS IN HUMAN BRAIN.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P155, doi. 10.1016/j.jalz.2018.06.2252
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- Publication type:
- Article
Histamine H<sub>3</sub> receptor in primary mouse microglia inhibits chemotaxis, phagocytosis, and cytokine secretion.
- Published in:
- Glia, 2015, v. 63, n. 7, p. 1213, doi. 10.1002/glia.22812
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- Publication type:
- Article
Molecular mechanism of histamine clearance by primary human astrocytes.
- Published in:
- Glia, 2013, v. 61, n. 6, p. 905, doi. 10.1002/glia.22484
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- Publication type:
- Article
Evaluation of <sup>18</sup>F labeled glial fibrillary acidic protein binding nanobody and its brain shuttle peptide fusion proteins using a neuroinflammation rat model.
- Published in:
- PLoS ONE, 2023, v. 17, n. 6, p. 1, doi. 10.1371/journal.pone.0287047
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- Publication type:
- Article
LONGITUDINAL ASSESSMENT OF [18F]THK-5351 ACCUMULATION IN PATIENTS WITH ALZHEIMER’S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P137, doi. 10.1016/j.jalz.2017.06.2560
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- Publication type:
- Article
SUCCESSFUL REDUCTION OF OFF-TARGET BINDING OF QUINOLINE DERIVATIVES AS TAU-SELECTIVE PET TRACERS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P136, doi. 10.1016/j.jalz.2017.06.2557
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- Publication type:
- Article
[F-18]THK5351 RETENTION IS ASSOCIATED WITH THE PROGRESSION OF BRAIN ATROPHY IN PATIENTS WITH ALZHEIMER’S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1094, doi. 10.1016/j.jalz.2016.06.2281
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- Publication type:
- Article
IDENTIFICATION OF WAVELENGTH-DEPENDENT COMPOUNDS FOR IMAGING LEWY PATHOLOGY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1136, doi. 10.1016/j.jalz.2016.07.012
- By:
- Publication type:
- Article
[F-18]THK5351 RETENTION IS ASSOCIATED WITH THE PROGRESSION OF BRAIN ATROPHY IN PATIENTS WITH ALZHEIMER’S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P138, doi. 10.1016/j.jalz.2016.06.222
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- Publication type:
- Article
Validation of the binding specificity of Tau PET tracer [18F]THK-5351 on postmortem human brain samples.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P271, doi. 10.1016/j.jalz.2015.06.190
- By:
- Publication type:
- Article
Validation of the binding specificity of Tau PET tracer [18F]THK-5351 on postmortem human brain samples.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P111, doi. 10.1016/j.jalz.2015.06.190
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- Publication type:
- Article
Distribution of tau pathology in the patients with mild cognitive impairment and Alzheimer’s disease measured with [18F]THK-5351 PET.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P791, doi. 10.1016/j.jalz.2015.06.189
- By:
- Publication type:
- Article
Distribution of tau pathology in patients with mild cognitive impairment and Alzheimer’s disease measured with [18F]THK-5351 PET.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P111, doi. 10.1016/j.jalz.2015.06.189
- By:
- Publication type:
- Article
Tau positron emission tomography images with a novel tracer, 18F-THK5351, in a patient with progressive supranuclear palsy.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P547, doi. 10.1016/j.jalz.2015.06.695
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- Publication type:
- Article
Wavelength-dependent selective detection of tau pathology in Alzheimer's disease using a novel fluorescent probe THK-1188
- Published in:
- 2012
- By:
- Publication type:
- Abstract
Novel 18F-labeled quinoline derivatives for in vivo detection of tau pathology in Alzheimer's disease
- Published in:
- 2012
- By:
- Publication type:
- Abstract
Near-infrared fluorescence probe X50 for in vivo detection of amyloid plaques in the brain
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Longitudinal Assessment of Tau Pathology in Patients with Alzheimer’s Disease Using [<sup>18</sup>F]THK-5117 Positron Emission Tomography.
- Published in:
- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140311
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- Publication type:
- Article
Tau PET Imaging in Alzheimer's Disease.
- Published in:
- Current Neurology & Neuroscience Reports, 2014, v. 14, n. 11, p. 1, doi. 10.1007/s11910-014-0500-6
- By:
- Publication type:
- Article
A Novel Near-Infrared Fluorescence Probe THK-565 Enables In Vivo Detection of Amyloid Deposits in Alzheimer's Disease Mouse Model.
- Published in:
- Molecular Imaging & Biology, 2023, v. 25, n. 6, p. 1115, doi. 10.1007/s11307-023-01843-4
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- Publication type:
- Article
Neuroimaging-pathological correlations of [<sup>18</sup>F]THK5351 PET in progressive supranuclear palsy.
- Published in:
- Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0556-7
- By:
- Publication type:
- Article
Characteristics of Tau and Its Ligands in PET Imaging.
- Published in:
- Biomolecules (2218-273X), 2016, v. 6, n. 1, p. 7, doi. 10.3390/biom6010007
- By:
- Publication type:
- Article
Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET.
- Published in:
- 2014
- By:
- Publication type:
- journal article
Non-invasive assessment of Alzheimer’s disease neurofibrillary pathology using 18F-THK5105 PET.
- Published in:
- Brain: A Journal of Neurology, 2014, v. 137, n. 6, p. 1762, doi. 10.1093/brain/awu064
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- Publication type:
- Article
Erratum to: Characterization of the radiolabeled metabolite of tau PET tracer 18F-THK5351.
- Published in:
- 2017
- By:
- Publication type:
- Erratum
Characterization of the radiolabeled metabolite of tau PET tracer F-THK5351.
- Published in:
- European Journal of Nuclear Medicine & Molecular Imaging, 2016, v. 43, n. 12, p. 2211, doi. 10.1007/s00259-016-3453-y
- By:
- Publication type:
- Article
[F]THK-5117 PET for assessing neurofibrillary pathology in Alzheimer's disease.
- Published in:
- European Journal of Nuclear Medicine & Molecular Imaging, 2015, v. 42, n. 7, p. 1052, doi. 10.1007/s00259-015-3035-4
- By:
- Publication type:
- Article
In vivo evaluation of a novel tau imaging tracer for Alzheimer's disease.
- Published in:
- European Journal of Nuclear Medicine & Molecular Imaging, 2014, v. 41, n. 5, p. 816, doi. 10.1007/s00259-013-2681-7
- By:
- Publication type:
- Article
Comparison of the binding characteristics of [F]THK-523 and other amyloid imaging tracers to Alzheimer's disease pathology.
- Published in:
- European Journal of Nuclear Medicine & Molecular Imaging, 2013, v. 40, n. 1, p. 125, doi. 10.1007/s00259-012-2261-2
- By:
- Publication type:
- Article
Monoamine oxidase B inhibitor, selegiline, reduces <sup>18</sup>F-THK5351 uptake in the human brain.
- Published in:
- Alzheimer's Research & Therapy, 2017, v. 9, p. 1, doi. 10.1186/s13195-017-0253-y
- By:
- Publication type:
- Article
Assessing THK523 selectivity for tau deposits in Alzheimer's disease and non Alzheimer's disease tauopathies.
- Published in:
- Alzheimer's Research & Therapy, 2014, v. 6, n. 1, p. 1, doi. 10.1186/alzrt240
- By:
- Publication type:
- Article
Preclinical Characterization of the Tau PET Tracer [ <sup>18</sup>F]SNFT-1: Comparison of Tau PET Tracers.
- Published in:
- Journal of Nuclear Medicine, 2023, v. 64, n. 9, p. 1495, doi. 10.2967/jnumed.123.265593
- By:
- Publication type:
- Article
Assessing reactive astrogliosis with <sup>18</sup>F-SMBT-1 across the Alzheimer’s disease spectrum.
- Published in:
- Journal of Nuclear Medicine, 2022, v. 63, n. 10, p. 1, doi. 10.2967/jnumed.121.263255
- By:
- Publication type:
- Article
First-in-human evaluation of <sup>18</sup>F-SMBT-1, a novel <sup>18</sup>F-labeled MAO-B PET tracer for imaging reactive astrogliosis.
- Published in:
- Journal of Nuclear Medicine, 2022, v. 63, n. 10, p. 1, doi. 10.2967/jnumed.121.263254
- By:
- Publication type:
- Article
Assessing reactive astrogliosis with <sup>18</sup>F-SMBT-1 across the Alzheimer’s disease spectrum.
- Published in:
- Journal of Nuclear Medicine, 2022, v. 63, n. 9, p. 1, doi. 10.2967/jnumed.121.263255
- By:
- Publication type:
- Article
First-in-human evaluation of 18F-SMBT-1, a novel <sup>18</sup>F-labeled MAO-B PET tracer for imaging reactive astrogliosis.
- Published in:
- Journal of Nuclear Medicine, 2022, v. 63, n. 9, p. 1, doi. 10.2967/jnumed.121.263254
- By:
- Publication type:
- Article
Assessing reactive astrogliosis with <sup>18</sup>F-SMBT-1 across the Alzheimer’s disease spectrum.
- Published in:
- Journal of Nuclear Medicine, 2022, v. 63, n. 7, p. 1, doi. 10.2967/jnumed.121.263255
- By:
- Publication type:
- Article
First-in-human evaluation of 18F-SMBT-1, a novel <sup>18</sup>F-labeled MAO-B PET tracer for imaging reactive astrogliosis.
- Published in:
- Journal of Nuclear Medicine, 2022, v. 63, n. 7, p. 1, doi. 10.2967/jnumed.121.263254
- By:
- Publication type:
- Article