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- Title
Role of AIM in Corynebacterium-induced granuloma formation in mice.
- Authors
Kuwata, Kazuhisa; Watanabe, Hisami; Yamamoto, Takashi; Miyazaki, Toru; Naito, Makoto
- Abstract
A conference paper on the role of apoptosis inhibitor expressed by macrophages (AIM) in Corynebacterium-induced granuloma formation in mice is presented. Results reveal the poor repopulation of natural killer T (NKT) cells in middle and late stages of granuloma formation in AIM-/-mice. Apoptosis of NKT cells and T cells was more prominent in AIM-/- mice. These findings indicate that AIM regulates NKT and T cell apoptosis and recruitment and plays a vital role in granuloma formation.
- Subjects
APOPTOSIS; MACROPHAGES; CUTIBACTERIUM acnes; GRANULOMA; KILLER cells; T cells
- Publication
Comparative Hepatology, 2004, Vol 3, p1
- ISSN
1476-5926
- Publication type
Conference Paper