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- Title
Two Androstane Derivatives from the Cultures of Fungus Marasmiellus ramealis (Bull.) Singer.
- Authors
Ning-Ning Yang; Qing-Yun Ma; Sheng-Zhuo Huang; Hao-Fu Dai; Zhi-Kai Guo; Zhi-Fang Yu; You-Xing Zhao
- Abstract
A new androstane derivative, 4β-methyl-15-oxa-14β-androstane-7-ene-4α-carboxylic acid (1) and a known one 4β-methyl-15-oxa-14β-androstane-7-ene-4α-hydroxyl (2) were isolated from the EtOAc extract of the cultures of the fungus Marasmiellus ramealis (Bull.) Singer. Their structures were elucidated on the basis of 1D and 2D NMR as well as MS spectroscopic data analysis. The inhibitory activity of two isolates against acetylcholinesterase (AChE) revealed that compound 1 exhibited definitely inhibitory activity.
- Subjects
ANDROSTANE; FERMENTATION; FUNGI; ACETYLCHOLINESTERASE inhibitors; PROTEASE inhibitors
- Publication
Bulletin of the Korean Chemical Society, 2014, Vol 35, Issue 11, p3224
- ISSN
0253-2964
- Publication type
Article
- DOI
10.5012/bkcs.2014.35.11.3224