We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Long-term outcomes of laparoscopic cholecystectomy: a prospective piecewise linear regression analysis.
- Authors
Hon-Yi Shi; Hao-Hsien Lee; Meng-Han Tsai; Chong-Chi Chiu; Yih-Huei Uen; King-Teh Lee
- Abstract
Background: The objectives of this study were to examine longitudinal time trends, to predict thresholds of improvement in each dimension of health-related quality of life (HRQoL), and to identify long-term predictors of HRQoL. Methods: This study analyzed 353 laparoscopic cholecystectomy (LC) patients. Disease-specific Gastrointestinal Quality-of-Life Index (GIQLI) and generic Short-Form 36-Item Health Survey (SF-36) scores were obtained immediately before surgery, then 3, 6, 12, and 24 months after surgery. Generalized estimating equations and piecewise linear regression models were used. Results: The examined population significantly ( p < 0.05) improved in both SF-36 and GIQLI subscale scores. The HRQoL dimensions were substantially improved the sixth month after surgery and continued improving until they reached a plateau at 54.93 to 73.18 months. The data also showed the following explanatory variables for HRQoL: time, age, gender, Charlson Comorbidity Index, and preoperative GIQLI and SF-36 subscale scores. Conclusions: As shown by the findings, the HRQoL scores improved substantially by the sixth month after surgery and continued improving until they reached a 4- to 7-year threshold, indicating that change trends in HRQoL dimensions may vary. Although HRQoL scores were substantially improved after cholecystectomy, the improvements were associated with preoperative functional status and demographic characteristics.
- Subjects
LAPAROSCOPIC surgery; CHOLECYSTECTOMY; REGRESSION analysis; EQUATIONS; COMORBIDITY; QUALITY of life
- Publication
Surgical Endoscopy & Other Interventional Techniques, 2011, Vol 25, Issue 7, p2132
- ISSN
1866-6817
- Publication type
Article
- DOI
10.1007/s00464-010-1508-x