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- Title
THE INFLUENCE OF BLOOD TRANSFUSION ON THE SHORT-TERM SURVIVAL OF LIVER TRANSPLANTATION PATIENTS.
- Authors
RODRIGUES NASCIMENTO, JOSÉ CARLOS; BRANCO CHAVES, VICTHOR CASTELO; CIDRÃO CAVALCANTE, LÍVIA; LIMA DA SILVA, ELIANA; ARAÚJO FERNANDES, THYAGO; ANDRAUS, WELLINGTON; CARNEIRO D'ALBUQUERQUE, LUIZ AUGUSTO
- Abstract
Orthotopic liver transplantation (OLT) has been established as the definitive treatment for terminal liver disease. Bleeding and transfusion requirements may worsen perioperative morbimortality. We proposed to evaluate the relationship between oneyear survival rate and transfusion of blood products in the perioperative OLT. Observational study involving 178 patients. The sample of patients was divided into two groups: the mortality group (MG), composed of patients who died within one-year post-OLT, and the survival group (SG), composed of those who remained alive at the end of the same period. The Model for End-Stage Liver Disease (MELD) score was higher in the MG (p<0.001). The number of units of RBCs and fresh-frozen plasma (FFP) was higher in the MG (p=0.010 and p=0.031, respectively). Mortality within one-year post-OLT was higher for those who received more than three units of RBCs (p=0.025) or FFP (p=0.005). One-year survival rate following OLT decreased significantly in association with the perioperative administration of over three units of RBCs or FFP. In the multivariate analysis, haemodialysis was an independent risk factor for increased mortality in the year post-OLT.
- Subjects
BLOOD transfusion; LIVER transplantation
- Publication
Brazilian Journal of Surgery & Clinical Research, 2021, Vol 36, Issue 2, p7
- ISSN
2317-4404
- Publication type
Article