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- Title
Formaldehyde exposure and patterns of concomitant contact allergy to formaldehyde and formaldehyde-releasers.
- Authors
Lundov, Michael D.; Johansen, Jeanne D.; Carlsen, Berit C.; Engkilde, Kåre; Menné, Torkil; Thyssen, Jacob P.
- Abstract
Background: Formaldehyde and formaldehyde-releasers are widely used in consumer products and may often cause contact allergy. Objective: To investigate the prevalence of concomitant contact allergy to formaldehyde and formaldehyde-releasers in dermatitis patients, and to determine the sources of formaldehyde exposure based on personal and occupational products obtained from dermatitis patients. Methods: Patch test data from referred dermatitis patients with a positive patch test reaction to formaldehyde or formaldehyde-releasers were analysed. For the period 2000–2008, the formaldehyde content in products obtained from formaldehyde-allergic patients was analysed by chromotropic acid test and/or acetylacetone test. Results: Patients allergic to a formaldehyde-releaser often had simultaneous contact allergy to formaldehyde. Other combinations were also prevalent. In patients who reacted to more than two formaldehyde-releasers, nearly all reacted simultaneously to formaldehyde. Seventy-five percent of the formaldehyde-allergic patients used a product that contained formaldehyde. The main source of formaldehyde exposure was cosmetics (78%). Conclusions: Concomitant contact allergy to formaldehyde and formaldehyde-releaser remains common. Furthermore, contact allergy to a formaldehyde-releaser was nearly always concomitant with another formaldehyde-releaser. Formaldehyde was commonly found in personal products used by formaldehyde-allergic patients.
- Subjects
FORMALDEHYDE; CONTACT dermatitis; COSMETICS; SKIN inflammation; DELAYED hypersensitivity
- Publication
Contact Dermatitis (01051873), 2010, Vol 63, Issue 1, p31
- ISSN
0105-1873
- Publication type
Article
- DOI
10.1111/j.1600-0536.2010.01745.x