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- Title
On the relative risk concept and TB morbidity in Russia: linking population genetics and epidemiological studies.
- Authors
RUDNEV, S. G.; SELITSKAYA, R. P.; BOLDYREVA, M. N.
- Abstract
A scheme relating population genetics and TB epidemiology data in Russia is proposed. For this, a genetic susceptibility index is suggested based on relative risk estimates and published data on genetic polymorphisms of various ethnic groups. The index correlates well ( r = 0.746, p < 0.05) with TB morbidity in genetically and geographically distant populations clearly indicating an important role of the genetic component in determining TB epidemiology in Russia.
- Subjects
RUSSIA; TUBERCULOSIS risk factors; POPULATION genetics; EPIDEMIOLOGY; GENETIC polymorphisms
- Publication
Russian Journal of Numerical Analysis & Mathematical Modelling, 2009, Vol 24, Issue 4, p377
- ISSN
0927-6467
- Publication type
Article
- DOI
10.1515/RJNAMM.2009.023